Brain Connectivity Lab

About

I am a researcher interested in using quantitative MRI, particularly (but not limited to) diffusion-weighted MRI, for the study of neurological disorders, with special interest in epilepsy. Along with the great people in the lab, we try to understand what causes some specific brain lesions to be epileptogenic, how this process evolves over time, and how it affects cognitive abilities. Some of these questions can be addressed in clinical research, but when it is not possible, we turn to animal models, where we have more control, and are able to use other methods on top of MRI. I joined the National Autonomous University of Mexico in 2010, and started the Brain Connectivity Laboratory in 2012. The type of work that I most enjoy is multidisciplinary by nature, and I have the fortune of having great collaborators.

Since 2014, I have led the National Laboratory for magnetic resonance imaging, which serves several research groups from all over Mexico. This has fortunately forced me to keep up with different quantitative MRI methods.

Interests

  • Epilepsy
  • Diffusion-weighted magnetic resonance imaging (dMRI)
  • Quantitative MRI

Education

  • Postdoc in imaging of epilepsy, 2008-2010

    Montreal Neurological Hospital

  • PhD in Biomedical Engineering / Medical Science, 2003-2007

    University of Alberta

  • Medical School, 1995-2002

    Universidad Autónoma de San Luis Potosí, Mexico

Brain Connectivity Laboratory

Researchers

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Luis Concha

Epilepsy, Diffusion-weighted magnetic resonance imaging (dMRI), Quantitative MRI

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Hiram Luna-Munguía

Epileptogenesis, Septo-hippocampal interaction

Staff

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Mirelta Regalado

Academic Technician

Grad Students

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Alejandra Garay

(Ph.D.) Role of the septo-hippocampal pathway in epileptogenesis (Hiram Luna)

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Daniela Bravo-Coutiño

(Ph.D.) Degeneration in regions of fiber crossings

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Fernando Hidalgo

(M.Sc.) Modulation of the septo-hippocampal pathway (Hiram Luna)

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Pamela García-Saldivar

(Ph.D.) Reorganization of cortex-basal ganglia circuits in response to rhythmic motor tasks in non-human primate (co-tutor).

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Antonio Aguilar-González

(M.Sc.) Modulation of the septo-hippocampal pathway (Hiram Luna)

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Edith Gaspar-Martínez

(Research assistant) Diffusion MRI to detect focal cortical dysplasias in patients with epilepsy.

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Leonardo Vázquez-Morales

(M.Sc.) Epilepsy and diabetes (Hiram Luna)

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Melissa García-Galindo

(M.Sc.) Longitudinal evaluation of cognitive performance in patients with temporal lobe epilepsy

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Olimpia Ortega-Fimbres

(M.Sc.) Detection of cortical dysplasia through advanced diffusion MRI.

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Priscila Ruiz-Acosta

(M.Sc.) Diffusion MRI to study the neocortical microstructure of the rat

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Yessenia García-Rizo

(M.Sc.) Quantification of myelin through MRI.

Alumni

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Raúl Rodríguez-Cruces

(Ph.D.) White matter integrity and its relation to cognitive performance in temporal lobe epilepsy patients.

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Alfonso Fajardo

(M.Sc.) Resting-state fMRI in temporal lobe epilepsy and its relation to cognitive abilities (co-tutor).

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Paulina Villaseñor

(M.Sc.) Diffusion characteristics of cortical dysplasia.

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Vicente Camacho-Téllez

(M.Sc.) Links between cognitive phenotypes and cortical activity during working memory in patients with TLE.

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Itzamná Sánchez-Moncada

Beat perception and entrainment. (Ph.D. Student in Hugo Merchant’s lab)

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Ana Aquiles

(Ph.D.) Anatomical and functional characterization of cortical displasias in an animal model

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Ricardo Coronado-Leija

(PDF) Analysis of white matter microstructure in crossing fiber regions through advanced models of DWI.

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Ricardo Ríos-Carrillo

(Ph.D.) Characterization of white matter microstructure using DWI with oscilating gradients.

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Luis Cuauhtémoc Márquez-Bravo

(M.Sc.) White matter alterations in relation to status epilepticus in a rat model of TLE.

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Omar Narvaez

(M.Sc.) Analysis of white matter microstructure in crossing fiber regions through histology and DWI (co-tutor).

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Guadalupe García-Gomar

(Ph.D.) Tractography of the pre-lemniscal radiations in Parkinson’s disease.

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Arafat Angulo-Perkins

(Ph.D.) Processing of complex acoustical stimuli in the auditory cortex.

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Gilberto Rojas-Vite

(M.Sc.) Microstrucutral correlates of advanced diffusion models.

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Laura Verónica Cuaya-Retana

(Ph.D.) Neural correlates of facial recognition in dogs through fMRI.

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Ana Elena Rosas-Carrera

(M.Sc.) Cognitive decline in temporal lobe epilepsy and its relation to fornix microsctructure.

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Circe Wilke

(M.Sc.) Cortical activity in response to rhythmic clarity of music stimuli

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Gabriela Castillo-López

(M.Sc.) White matter microstructure and its correlation to concentration of alpha-synuclein in skin.

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Luis Octavio Jiménez-Valverde

(M.Sc.) Working memory in TLE

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Rafael Moreno Salazar

(M.Sc.) Cortical atrophy in patients with TLE and its relation to cognitive abilities

Posts

Opportunities in the lab

Interested in doing your M.Sc. or Ph.D? Contact us! We are currently seeking motivated graduate students to work in the fields of epileptogenesis and brain imaging. We do not encourage a specific academic profile, as we believe it has very little predictive value about an individual’s future skills.

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