Neuroscience, Learning and Memory
Keywords: memory, learning, glucocorticoids, noradrenaline, stress hormones, striatum, amygdala, hippocampus
Our research goals are mainly oriented to studying the involvement of adrenal stress hormones, and their relationship to several neurotransmitters (acetylcholine, GABA, serotonin, endocannabinoids, etc.) in a memory system that includes the striatum, a basal ganglion involved in memory consolidation that has glucocorticoid receptors, as well as the amygdala hippocampus, and cerebral cortex. Thus, the main activities of our laboratory consist of: a) performing stereotactic surgery for implantation of cannulas in several brain structures; b) using behavioral techniques such as inhibitory avoidance, water maze, the context or tone fear conditioning, Tolman maze, object recognition, motor behavior, etc.; c) systemic or intracranial administration of drugs; d) protein detection techniques including brain slicing, WesternBlots, ELISAs and immunohistochemistry; e) statistical analysis of the data obtained; f) publishing the results obtained; and g) the constant discussion of the literature of the field.
We are a consolidated group studying the relationships of stress with learning and memory processes. We keep productive collaborative projects with colleagues from both local and foreign institutions that have allowed for important contributions to our field of study. We would like to continue with the formulation and development of ideas and research programs that may contribute to the generation of scientific knowledge.